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A clinical trial investigated the effect of 8-week metformin treatment on aging individuals with mild cognitive impairment (MCI) or early AD, and the results revealed that metformin is associated with improved executive function, companied by improvement in learning/memory and attention [27]

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J Diab Invest 2021;12:203448

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Neuroendocrine Appetite Regulation and Hormonal Timing Contemporary scientific research has heavily focused on the extended activity profile of this dual agonist, which actively enables sustained receptor engagement and remarkably prolonged metabolic signaling in experimental settings